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Research

We have research fellows attached to The Registry who carry out research on polyposis syndromes as part of their PhD work

What projects are we currently working on?

Isabel Martin’s project is focused on the role of environmental factors on duodenal and pouch polyps in FAP. She will be using advanced methods of genetic testing and novel technologies to analyse fluid and tissue samples.

Chukwuemeka Anele’s area of research is inherited bowel cancer which includes evaluating methods of identifying Lynch syndrome on tissue samples such as endoscopic biopsies, lymph nodes or metastatic tissues; establishing a correlation between circulating tumour cell numbers and time to progression of bowel cancer in FAP and assessing the feasibility of remote monitoring of patients in the early post-operative period following elective bowel surgery.

Salman Rana is researching Serrated Polyposis Syndrome and working in collaboration with the Wellcome Centre in Oxford to try and find a genetic cause for this condition.

What other work are we involved with?

The Polyposis Registry is the secretariat for InSiGHT – The International Society for Gastrointestinal Hereditary Tumours. This is an international, multidisciplinary, scientific organisation. Their aim is to improve the quality of care of patients and families with any hereditary condition resulting in gastrointestinal tumours. Take a look at more of their work on the InSight Group website.